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- The lymphatic system contains a network of vessels that assists in
circulating body fluids.
- The lymphatic system defends the body from foreign invasion by disease
causing agents such as viruses, bacteria, or fungi.
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- Lymph fluid acts as intermediary between blood, capillaries, and tissues
- Lymph vessels transport tissue fluid back into circulatory system
- Lymph nodes produce lymphocytes and filter harmful bacteria
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- Spleen produces lymphocytes and monocytes, acts as a reservoir for
blood, and recycles red blood cells
- Thymus gland produces T-lymphocytes for immune system
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- Lymph diffuses from capillaries into tissue spaces
- Lymph acts as an intermediary between blood in capillaries and tissues
- Lymph carries digested food, oxygen, and hormones to cells
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- Lymph vessels accompany and are similar to veins
- They are in almost all tissues and organs that have blood vessels
- Lymph only travels in direction from body organs to the heart
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- 2 large main lymphatics
- Thoracic duct (left lymphatic duct)
- Receives lymph from left side of head, neck, abdominal area, and lower
limbs
- Right lymphatic duct
- Circulates lymph from right arm, right side of head, and upper trunk
to the superior vena cava
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- Lymph nodes provide sites for lymphocyte production and screen harmful
substances from the lymph
- Bacteria and other harmful substances in large quantities may injure the
lymph node
- Adenitis - swelling in lymph gland
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- Tonsils are masses of lymphatic tissues capable of producing lymphocytes
and filtering bacteria
- Three pairs of tonsils
- Palatine
- Adenoids
- Lingual
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- The spleen is a saclike mass of lymphatic tissue that forms lymphocytes
and monocytes
- The spleen filters blood that passes through it, destroying old or
fragile red blood cells
- The spleen stores large amounts of red blood cells
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- The thymus’s function is to produce lymphocytes called T-lymphocytes
- The thymus is also an endocrine gland because it secretes a hormone
called thymosin that stimulates the production of lymphoid cells
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- Lymphadenitis - enlargement of the lymph nodes that occurs when
infection is present
- Hodgkin’s disease - form of cancer of lymph nodes
- Infectious mononucleosis - caused by Epstein-Barr virus
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- Immunity is the body’s ability to resist invaders and disease
- Acquired immunity - reaction to exposure of invaders
- Passive acquired immunity - borrowed immunity from another person’s
blood that produces immunity immediately
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- Active acquired immunity
- Natural acquired immunity results from having had and recovering from
disease
- Artificial acquired immunity is the result of inoculation with
vaccine, antigen, or toxoid
- Immunization is increasing the resistance to infection through
artificial means
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- Autoimmunity
- Occurs when a person’s own immune system targets normal cells, tissues,
and organs of person’s own body
- Causes range from genetics to viruses to sunlight exposure
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- Hypersensitivity
- Body’s immune system fails to protect itself against foreign material
- Antibodies irritate certain body cells
- Allergen - antigen causes allergic responses
- Anaphylactic shock - severe, often fatal allergic reaction
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- Acquired - disease is not inherited
- Immune - body’s natural defenses
- Deficiency - lacks cellular immunity
- Syndrome - diagnosed from sets of diseases or conditions present
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- Human immunodeficiency virus (HIV) destroys T4-lymphocyte cells without
causing symptoms
- Opportunistic infections arise
- Three outcomes of HIV infection:
- AIDS
- AIDS-related complex (ARC)
- Asymptomatic infection
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- Transmission of AIDS
- Sexual contact with infected partner
- Sharing hypodermic needles among IV drug users
- In utero or at birth of infected mother
- Transfusion of blood
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- Screening tests for HIV/AIDS
- There are two antibody tests
- Enzyme-linked immunosorbent assay (ELISA) - detects antibodies for
AIDS but not the virus
- Western blot is the follow-up to confirm ELISA results
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- Symptoms of HIV/AIDS
- Flu-like symptoms
- Fever
- Headache
- Malaise - generalized feeling of discomfort, illness, or lack of
well-being that can be associated with a disease state.
- Enlarged lymph glands
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- There is no cure for AIDS yet certain drugs are used to slow the virus
- Transmission is prevented by following the CDC’s Standard Precautions
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