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THE LYMPHATIC SYSTEM AND IMMUNITY
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WHAT IS THE LYMPHATIC SYSTEM?
  • The lymphatic system contains a network of vessels that assists in circulating body fluids.
  • The lymphatic system defends the body from foreign invasion by disease causing agents such as viruses, bacteria, or fungi.
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FUNCTIONS OF THE LYMPHATIC SYSTEM
  • Lymph fluid acts as intermediary between blood, capillaries, and tissues
  • Lymph vessels transport tissue fluid back into circulatory system
  • Lymph nodes produce lymphocytes and filter harmful bacteria
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FUNCTIONS OF THE LYMPHATIC SYSTEM
  • Spleen produces lymphocytes and monocytes, acts as a reservoir for blood, and recycles red blood cells
  • Thymus gland produces T-lymphocytes for immune system
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LYMPH
  • Lymph diffuses from capillaries into tissue spaces
  • Lymph acts as an intermediary between blood in capillaries and tissues
  • Lymph carries digested food, oxygen, and hormones to cells
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LYMPH VESSELS
  • Lymph vessels accompany and are similar to veins
  • They are in almost all tissues and organs that have blood vessels
  • Lymph only travels in direction from body organs to the heart
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LYMPH VESSELS
  • 2 large main lymphatics
    • Thoracic duct (left lymphatic duct)
      • Receives lymph from left side of head, neck, abdominal area, and lower limbs
    • Right lymphatic duct
      • Circulates lymph from right arm, right side of head, and upper trunk to the superior vena cava

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LYMPH NODES
  • Lymph nodes provide sites for lymphocyte production and screen harmful substances from the lymph
  • Bacteria and other harmful substances in large quantities may injure the lymph node
  • Adenitis - swelling in lymph gland
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LYMPH NODES
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TONSILS
  • Tonsils are masses of lymphatic tissues capable of producing lymphocytes and filtering bacteria
  • Three pairs of tonsils
    • Palatine
    • Adenoids
    • Lingual
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SPLEEN
  • The spleen is a saclike mass of lymphatic tissue that forms lymphocytes and monocytes
  • The spleen filters blood that passes through it, destroying old or fragile red blood cells
  • The spleen stores large amounts of red blood cells
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THYMUS GLAND
  • The thymus’s function is to produce lymphocytes called T-lymphocytes
  • The thymus is also an endocrine gland because it secretes a hormone called thymosin that stimulates the production of lymphoid cells
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DISORDERS OF THE
LYMPH SYSTEM
  • Lymphadenitis - enlargement of the lymph nodes that occurs when infection is present
  • Hodgkin’s disease - form of cancer of lymph nodes
  • Infectious mononucleosis - caused by Epstein-Barr virus
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IMMUNITY
  • Immunity is the body’s ability to resist invaders and disease
    • Acquired immunity - reaction to exposure of invaders
    • Passive acquired immunity - borrowed immunity from another person’s blood that produces immunity immediately


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IMMUNITY
    • Active acquired immunity
      • Natural acquired immunity results from having had and recovering from disease
      • Artificial acquired immunity is the result of inoculation with vaccine, antigen, or toxoid
    • Immunization is increasing the resistance to infection through artificial means
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IMMUNITY
  • Autoimmunity
    • Occurs when a person’s own immune system targets normal cells, tissues, and organs of person’s own body
    • Causes range from genetics to viruses to sunlight exposure


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IMMUNITY
  • Hypersensitivity
    • Body’s immune system fails to protect itself against foreign material
    • Antibodies irritate certain body cells
    • Allergen - antigen causes allergic responses
      • Anaphylactic shock - severe, often fatal allergic reaction
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AIDS/HIV
  • Acquired - disease is not inherited
  • Immune - body’s natural defenses
  • Deficiency - lacks cellular immunity
  • Syndrome - diagnosed from sets of diseases or conditions present
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AIDS/HIV
  • Human immunodeficiency virus (HIV) destroys T4-lymphocyte cells without causing symptoms
  • Opportunistic infections arise
  • Three outcomes of HIV infection:
    • AIDS
    • AIDS-related complex (ARC)
    • Asymptomatic infection
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AIDS/HIV
  • Transmission of AIDS
    • Sexual contact with infected partner
    • Sharing hypodermic needles among IV drug users
    • In utero or at birth of infected mother
    • Transfusion of blood
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AIDS/HIV
  • Screening tests for HIV/AIDS
    • There are two antibody tests
      • Enzyme-linked immunosorbent assay (ELISA) - detects antibodies for AIDS but not the virus
      • Western blot is the follow-up to confirm ELISA results
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AIDS/HIV
  • Symptoms of HIV/AIDS
    • Flu-like symptoms
    • Fever
    • Headache
    • Malaise - generalized feeling of discomfort, illness, or lack of well-being that can be associated with a disease state.
    • Enlarged lymph glands

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AIDS/HIV
  • There is no cure for AIDS yet certain drugs are used to slow the virus
  • Transmission is prevented by following the CDC’s Standard Precautions